Study of myofibroblast differentiation

monitoring the effect of extracellular vesicles / exosomes on myofibroblast differentiation in a model using TGFß as inducer of alpha smooth muscle actin in fibroblasts

application: identification of extracellular vesicles that influence myofibroblast differentiation during wound healing, fibrosis, and fibrocontractive diseases

Recent_Highlights_EVS2

treatment of telomerized human fibroblasts fHDF/TERT166 with transforming growth factor beta (TGFß) and induction of alpha smooth muscle actin (𝛂-SMA) expression (immunofluorescence staining, cell nuclei are counterstained with DAPI)

fHDF:TERT166

reduction of 𝛂-SMA upon treatment with extracellular vesicles from Wharton´s Jelly MSCs

By admin|2021-04-08T10:30:58+00:00March 29th, 2021|recent highlights EV|

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