Analysis of miRNA cargo of extracellular vesicles from Wharton´s Jelly derived mesenchymal stem cells WJ-MSC/TERT273

application: characterization and quality control for stable production of extracellular vesicles

lab-scale production of extracellular vesicles from human telomerized cells (WJ-MSC/TERT273) using a hollow fiber bioreactor system, continuous production over a period of at least 4 months, enrichment of EVs using tangential flow filtration

characterization of extracellular vesicles harvested at different time points during production by analysis of miRNA cargo, stable miRNA cargo throughout the whole production process was observedWharton´s Jelly MSCs.