Study of myofibroblast differentiation
monitoring the effect of exogenous factors on myofibroblast differentiation in a model using TGFß as inducer of alpha smooth muscle actin in fibroblasts
application: identification of drugs that influence myofibroblast differentiation during wound healing, fibrosis and fibrocontractive diseases
![Recent_Highlights_EVS2](https://evercyte.com/wp-content/uploads/2021/03/Recent_Highlights_EVS2.jpg)
treatment of telomerized human fibroblasts fHDF/TERT166 with transforming growth factor beta (TGFß) and induction of alpha smooth muscle actin (𝛂-SMA) expression (immunofluorescence staining, cell nuclei are counterstained with DAPI)
![reduction of 𝛂-SMA upon treatment with extracellular vesicles from Wharton´s Jelly MSCs](https://evercyte.com/wp-content/uploads/2021/04/Bildschirmfoto-2021-04-08-um-12.22.36.png)
reduction of 𝛂-SMA upon treatment with extracellular vesicles from Wharton´s Jelly MSCs