3D spheroid assay for screening of angiogenesis modulators

monitoring the effect of exogenous factors on sprout formation from endothelial spheroids as a measure for induction / inhibition of angiogenesis

application: identification of drugs that modify angiogenesis / treatment option for vascular malfunction-associated diseases / boosting of angiogenesis for tissue regeneration

analysis of length and number of sprouts from individual spheroids treated with vascular endothelial growth factor and cyclosporin-A