Analysis of miRNA cargo of extracellular vesicles from Wharton´s Jelly derived mesenchymal stem cells WJ-MSC/TERT273
application: characterization and quality control for stable production of extracellular vesicles
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lab-scale production of extracellular vesicles from human telomerized cells (WJ-MSC/TERT273) using a hollow fiber bioreactor system, continuous production over a period of at least 4 months, enrichment of EVs using tangential flow filtration
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characterization of extracellular vesicles harvested at different time points during production by analysis of miRNA cargo, stable miRNA cargo throughout the whole production process was observedWharton´s Jelly MSCs.