3D spheroid assay for screening of modulation of angiogenesis
monitoring the effect of extracellular vesicles on sprout formation from endothelial spheroid
application: identification of extracellular vesicles that modify angiogenesis / treatment option for vascular malfunction-associated diseases
![3D speroidassay](https://evercyte.com/wp-content/uploads/2021/03/3D-speroidassay.png)
cultivation of telomerized human umbilical vein endothelial cells HUVEC/TERT2 as spheroids in hanging drops; embedding of spheroids into semi-sold matrix
![Recent_Highlights_EVS](https://evercyte.com/wp-content/uploads/2021/03/Recent_Highlights_EVS.jpg)
treatment of spheroids with vascular endothelial growth factor (VEGF), extracellular vesicles from endothelial cells or Wharton´s Jelly derived MSCs, induction of sprout formation by VEGF and EVs from WJ-MSC/TERT273 cells