Services

senolytic/senomorphic drug testing

Senolytics, agents selectively inducing apoptosis in senescent cells that accumulate in tissues with ageing, are now considered game changers across a range of age-associated diseases, including frailty, cardiac dysfunction, vascular hyperreactivity and calcification, diabetes mellitus, liver steatosis, osteoporosis, vertebral disk degeneration, and pulmonary fibrosis. Senolytic agents are being tested in several proof-of-concept clinical trials.

Increased focus on senolytics and senomorphics/senostatics (suppression of senescence markers or preventing secondary senescence), brings the need for new tools to identify novel agents and elucidate their modes of action, including drug screening with relevant and standardizable in vitro models. Evercyte offers a fast-track development route from initial senolytic candidate hit to lead cell-based testing.

Related Services

characterization of primary and immortalized human cells

LF/TERT309

Relevant and standardizable pulmonary fibroblast cell line

MSCs for production of clinical grade extracellular vesicles

Customer Reviews

“I have had the pleasure of working with Evercyte for the last few years. We continually rely on Evercyte because of the high-quality data that they produce, their diligent responsiveness, and their excellent customer service.”

 

Josh Garlich, Senior Research Scientist, Apellis Pharmaceuticals, Inc.

"Cytonus has been working with Evercyte from many years as they are a trusted partner and have always delivered the highest quality cell lines to advance our platform.  We routinely draw on their expertise to meet cellular engineering challenges and they have not disappointed."

Remo Moomiaie-Qajar, Cytonus Therapeutics, Inc.

all about our
EV cell factories

fHDF/TERT166

human telomerized fibroblasts for testing novel compounds for senolytic activities

human telomerized lung fibroblasts coming soon

Related Services

characterization of primary-like, hTERT immortalized human cells for expression of cell type specific markers and functional properties

Customer Reviews

“I have had the pleasure of working with Evercyte for the last few years. We continually rely on Evercyte because of the high-quality data that they produce, their diligent responsiveness, and their excellent customer service.”

 

Josh Garlich, Senior Research Scientist, Apellis Pharmaceuticals, Inc.

"Cytonus has been working with Evercyte from many years as they are a trusted partner and have always delivered the highest quality cell lines to advance our platform.  We routinely draw on their expertise to meet cellular engineering challenges and they have not disappointed."

Remo Moomiaie-Qajar, Cytonus Therapeutics, Inc.