Are telomerized cells tumorigenic?
Ectopic expression of the catalytic subunit of human telomerase hTERT does not induce a tumorigenic conversion of the cells. The cells do not form colonies when seeded into
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12, 2021
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12, 2021
Does overexpression of hTERT change the cellular phenotype?
Ectopic expression of the catalytic subunit of human telomerase hTERT leads to an extension of the cellular life span while maintaining cell type specific markers and functions. Therefore,
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12, 2021
How long can the normal cells be propagated in vitro?
The number of population doublings that can be performed strongly depends on several parameters such as the cell type, the culture conditions as well as the number of